The design of urban systems that allow growth while also maximising ecosystem services is identified as an important priority for creating a Good Anthropocene. An ecosystem service (ES)-based approach to landscape interventions maximises the provision of ESs, and in doing so, repairs and reinforces threatened ecological planetary boundaries. As an urbanising planet, cities are critical frontiers of human interaction with these planetary boundaries, and therefore a critical arena for ES-based intervention. Globally, the predominant pattern of urbanisation is dedensification, an outwardly expanding trend where cities are growing in physical extent at a higher rate than their population growth. We therefore require spatially explicit tools capable of reconciling dedensification and Good Anthropocene visions. We propose a methodology that integrates agroecology and urbanisation and is focussed specifically on the supply of targeted regulating ESs. This ‘Agroecology for the City’ differs from conventional urban agriculture discourse and its preoccupation with food security. Our research interest is agroecological farm systems’ (AFSs) capacity to provide critical life support services in a spatially effective manner to urban systems. Our recent research introduced a new GIS-based model (ESMAX) and a spatial agroecology approach that identified AFS configurations at a 1 ha scale which maximised the supply of three regulating ESs, as well as multifunctional performance across all three ESs combined. In the present research, we apply this process at a larger scale, with 1 ha and 4 ha AFS parcels being integrated with a real-world 200 ha peri-urban residential development. The AFS parcels and built-up areas are configured differently to maximise the supply of ESs identified as critical by the local community. We found that arrangements with AFS parcels interspersed evenly with built-up areas provided the best multifunctionality across the four ESs tested. This supports pathways for a Good Anthropocene that work with the global urbanising reality of dedensification and underpin the need for a hybrid science of rural/urban systems.