The nonparametric method of dynamic data envelopment analysis (DDEA) has become increasingly popular for conducting comparative efficiency evaluations. In recent years, dynamic data envelopment analysis (DDEA), a variant of this method, has gained significant attention. This article applies dynamic analysis to evaluate the efficiency of the research sector in Russian regions. Traditional input variables such as the number of research staff and R&D expenditure are considered, while publication and patent metrics serve as output indicators. The analysis covers a substantial time period, spanning from 2009 to 2020. Notably, the proposed evaluation method incorporates publication quality measures as a carry-over variable, in addition to accumulated R&D expenditure. The study employs dynamic data envelopment analysis to compare the obtained results with previous evaluations of the research and technology sector in Russian regions. The findings demonstrate that the proposed method serves as a valuable ranking technique, enhancing existing evaluations of regions’ research and technology potential in terms of efficiency. The article concludes by discussing the prospects and limitations of the method in evaluating and forecasting research and technology profiles of regions.