Temperature control is the common problems in the process of industrial production. Because the temperature system is a kind of time-varying nonlinear system, this gives the temperature real-time control has brought the certain difficulty. In order to solve this problem, this paper designed a kind of self-tuning PID control system. It puts the model parameter online identification and controller online design organic unifies in together, parameter identification using fading memory recursive least squares algorithm, and the controller adopts the pole assignment algorithm. This makes the control system not only can online real-time adjustment of parameters, but also ensure that the actual closed-loop system converges to zero pole expectations of zero pole, achieve good control effect. At the same time, aiming at the limitation of the cable temperature measurement technology, this paper designs the wireless acquisition function of multipoint temperature. Simulation results prove the effectiveness of the proposed method.