This paper aims to analyse death and injury frequencies caused by road accidents in different regions of Ukraine. Types of road accidents and their degree of severity are analyzed, in addition to the level of road accidents in Ukraine compared to the same parameters in Europe. 2007 and 2013 death rates and injury rates due to car crashes or traffic accidents are considered as ratio per 1,000 inhabitants and 1,000 cars. An overall geographically featured assessment of road injuries has also been computed for each administrative region of the country. An evaluation of an integrated road safety index based on the statistical analysis of road accidents indicators has been developed (primarily making use of factor analysis such as principal component analysis and correlation analysis). Assessment of an integrated road safety index has been introduced since this enabled us to differentiate and identify a variety of regional categories related to traumatism and mortality rates due to road accidents.