Powered by OpenAIRE graph
Found an issue? Give us feedback
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Clinical Immunology ...arrow_drop_down
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
Clinical Immunology Communications
Article . 2022 . Peer-reviewed
License: CC BY
Data sources: Crossref
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
https://dx.doi.org/10.60692/8z...
Other literature type . 2022
Data sources: Datacite
https://dx.doi.org/10.60692/hc...
Other literature type . 2022
Data sources: Datacite
versions View all 4 versions
addClaim

This Research product is the result of merged Research products in OpenAIRE.

You have already added 0 works in your ORCID record related to the merged Research product.

Hepatitis E virus sero-prevalence among pregnant women in Khyber Pakhtunkhwa Pakistan

الانتشار المصلي لفيروس التهاب الكبد E بين النساء الحوامل في خيبر باختونخوا باكستان
Authors: Shahzad Ahmad Khan; Zafran Khan; Zahoor Alam; Haris Sana; Muhammad Ali; Nasib Zaman; Daniya Ualiyeva; +2 Authors

Hepatitis E virus sero-prevalence among pregnant women in Khyber Pakhtunkhwa Pakistan

Abstract

Au Pakistan, le virus de l'hépatite E (VHE) est répandu. L'exposition au VHE est mortelle pendant la grossesse, avec des taux d'infection élevés chez la mère et le bébé, même dans des situations asymptomatiques. La chercheuse a examiné des femmes enceintes séronégatives pour le VHE présentant une hépatite aiguë ou une augmentation des évaluations des caractéristiques rénales sur 12 sites médicaux à Khyber Pakhtunkhwa, au Pakistan, afin d'identifier les risques de maladie maternelle et fœtale d'août à décembre 2018. À l'exception d'une pendant toute la grossesse, vingt-cinq des 135 femmes étaient exemptes de VHE et en période périnatale. L'infection par le VHE a été observée chez 0,19 % des femmes nouvellement enceintes. En outre, 11 cas d'induction forcée du travail, 7 cas de travail normal, 5 cas de travail normal (à terme), 2 cas de décès et 1 cas de décès intra-utérin ont été signalés avant d'aller chez le médecin, une fille ayant subi un avortement. Il y a eu huit décès post-partum : cinq dus à des infections, quatre à des fausses couches et deux à des fausses couches. Alors que 18 mères qui ont survécu à des avortements volontaires ou intentionnels et trois femmes qui ont continué à tomber enceintes mais qui n'ont pas accouché sont décédées à la suite d'un avortement. La présente étude a révélé que l'infection par le VHE pendant la grossesse augmentait le taux de mortalité de 14,2 %.

En Pakistán, el virus de la hepatitis E (VHE) es prevalente. La exposición al VHE es mortal durante el embarazo, con altas tasas de infección tanto en la madre como en el bebé, incluso en situaciones asintomáticas. El investigador examinó a mujeres embarazadas negativas al VHE con hepatitis aguda o aumento de las evaluaciones de las características renales en 12 centros médicos en Khyber Pakhtunkhwa, Pakistán, para identificar los riesgos de enfermedad materna y fetal de agosto a diciembre de 2018. Excepto una durante todo el embarazo, veinticinco de las 135 mujeres estaban libres de HEV y en el período perinatal. Se encontró infección por VHE en el 0,19% de las mujeres recién embarazadas. Asimismo, se reportaron 11 casos de inducción forzada del parto, 7 casos de parto normal, 5 casos de parto normal (a término), 2 casos de muerte y 1 caso de muerte intrauterina antes de acudir al médico una niña tuvo un aborto. Hubo ocho muertes posparto: cinco por infecciones, cuatro por abortos espontáneos y dos por abortos espontáneos. Mientras que 18 madres que sobrevivieron a abortos inducidos voluntaria o intencionalmente y tres mujeres que continuaron quedando embarazadas pero no dieron a luz murieron como resultado del aborto. El estudio actual encontró que la infección por VHE durante el embarazo aumentó la tasa de mortalidad en un 14,2%.

In Pakistan, the Hepatitis E virus (HEV) is prevalent. HEV exposure is deadly during pregnancy, with high infection rates in both the mother and the baby, even in asymptomatic situations. The researcher examined HEV-negative pregnant women with acute hepatitis or increased renal characteristic assessments at 12 medical sites in Khyber Pakhtunkhwa, Pakistan, to identify maternal and fetal disease risks from August to December 2018. Except for one during the entire pregnancy, twenty-five of the 135 females were HEV-free and in the perinatal period. HEV infection was found in 0.19% of newly pregnant women. Also, 11 cases of forcible induction of labor, 7 cases of normal labor, 5 cases of normal labor (full-term), 2 cases of death, and 1 case of intrauterine death were reported before going to the doctor a girl had an abortion. There were eight postpartum deaths: five from infections, four from miscarriages, and two from miscarriages. While 18 mothers who survived voluntarily or intentionally induced abortions and three women who continued to get pregnant but did not deliver died as a result of abortion. The current study found that HEV infection during pregnancy raised the death rate by 14.2%.

في باكستان، ينتشر فيروس التهاب الكبد E (HEV). يكون التعرض لفيروس HEV مميتًا أثناء الحمل، مع ارتفاع معدلات العدوى في كل من الأم والطفل، حتى في المواقف التي لا تظهر عليها أعراض. فحص الباحث النساء الحوامل المصابات بالتهاب الكبد الحاد أو زيادة تقييمات الخصائص الكلوية في 12 موقعًا طبيًا في خيبر باختونخوا، باكستان، لتحديد مخاطر أمراض الأم والجنين من أغسطس إلى ديسمبر 2018. باستثناء واحدة خلال فترة الحمل بأكملها، كانت خمسة وعشرون من 135 أنثى خالية من فيروس HEV وفي فترة ما حول الولادة. تم العثور على عدوى فيروس الالتهاب الكبدي الوبائي في 0.19 ٪ من النساء الحوامل حديثًا. كما تم الإبلاغ عن 11 حالة من التحريض القسري للمخاض، و 7 حالات من المخاض الطبيعي، و 5 حالات من المخاض الطبيعي (كامل المدة)، وحالتين من الوفاة، وحالة واحدة من الوفاة داخل الرحم قبل الذهاب إلى الطبيب. كانت هناك ثماني وفيات بعد الولادة: خمس من العدوى، وأربع من الإجهاض، واثنتان من الإجهاض. في حين توفيت 18 أمًا نجين من الإجهاض الطوعي أو المتعمد وثلاث نساء استمرن في الحمل ولكن لم يلدن نتيجة للإجهاض. وجدت الدراسة الحالية أن عدوى فيروس الالتهاب الكبدي الوبائي أثناء الحمل رفعت معدل الوفيات بنسبة 14.2 ٪.

Keywords

Emergency Medical Services, Liver Cirrhosis and Associated Complications, Genotype, Population, Immunology, Health Professions, Pediatrics, Biochemistry, Gene, Hepatitis, Sociology, Pregnancy, Health Sciences, Hepatitis E virus, Genetics, Hepatitis E Infection and Treatment, Challenges and Solutions in Rural Health Workforce, Biology, Hepatology, FOS: Clinical medicine, Abortion, Maternal death, RC581-607, Khyber pakhtunkhwa, Asymptomatic, FOS: Sociology, Obstetrics, Therapeutic abortion, Chemistry, Environmental health, Socioeconomics, FOS: Biological sciences, Medicine, Surgery, Immunologic diseases. Allergy

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    2
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
2
Average
Average
Average
gold