In this paper we describe our approach to the VAST Challenge Mini Challenge 3 which provided time-series multispectral image for visualization and analysis. We used Matlab for rapid prototyping, interface design and implementation of the final software. The resulting application, Multilab, allowed us to interactively explore the collection of multispectral images, generate and test hypotheses, and answer quantitative questions about the images. Index Terms: I.4.9 [Computing Methodologies]: Image Processing and Computer Vision—Applications; D.2.2 [Software]: Software Engineering–Design Tools and Techniques;