Akinetic crisis and withdrawal syndromes: guideline “Parkinson’s disease” of the German Society of Neurology
Copyright policy )Akinetic crisis and withdrawal syndromes: guideline “Parkinson’s disease” of the German Society of Neurology
AbstractThe akinetic crisis is a well-known, rare, potentially life-threatening condition in Parkinson’s disease with subacute worsening of akinesia, rigidity, fever, impaired consciousness, accompanying vegetative symptoms and transient dopa-resistance. The akinetic crisis was historically supposed to be a “withdrawal syndrome” in the sense of discontinuation of dopaminergic medication. Recently, other “withdrawal syndromes” as the specific “dopamine agonist withdrawal syndrome” or “deep brain stimulation withdrawal syndrome” have been described as emergency situations with specific subacute symptom constellations. All three conditions require immediate start of the adequate therapy to improve the prognosis. Here, the diagnostic criteria and treatment options of these three acute, severely disabling syndromes will be reported along the current guidelines of the German Parkinson Guideline Group.
Akinetic crisis, therapy [Parkinson Disease], Deep brain stimulation withdrawal syndrome, German Parkinson Guideline, Diagnostic criteria, diagnosis [Substance Withdrawal Syndrome], Deep Brain Stimulation, Review, Dopamine agonist withdrawal syndrome, Antiparkinson Agents, Germany, standards [Societies, Medical], adverse effects [Antiparkinson Agents], Humans, Societies, Medical, therapeutic use [Antiparkinson Agents], Parkinson Disease, drug therapy [Parkinson Disease], Substance Withdrawal Syndrome, Neurology, standards [Deep Brain Stimulation], standards [Neurology], standards [Practice Guidelines as Topic], Practice Guidelines as Topic, Antiparkinson Agents/therapeutic use [MeSH] ; Deep Brain Stimulation/standards [MeSH] ; Humans [MeSH] ; Therapy ; Parkinson Disease/therapy [MeSH] ; Antiparkinson Agents/adverse effects [MeSH] ; Practice Guidelines as Topic/standards [MeSH] ; Parkinson Disease/diagnosis [MeSH] ; Neurology/standards [MeSH] ; Parkinson Disease/drug therapy [MeSH] ; Deep brain stimulation withdrawal syndrome ; Akinetic crisis ; Societies, Medical/standards [MeSH] ; Germany [MeSH] ; Dopamine agonist withdrawal syndrome ; Review ; Substance Withdrawal Syndrome/diagnosis [MeSH] ; German Parkinson Guideline ; Diagnostic criteria, Therapy, diagnosis [Parkinson Disease], ddc: ddc:610
Akinetic crisis, therapy [Parkinson Disease], Deep brain stimulation withdrawal syndrome, German Parkinson Guideline, Diagnostic criteria, diagnosis [Substance Withdrawal Syndrome], Deep Brain Stimulation, Review, Dopamine agonist withdrawal syndrome, Antiparkinson Agents, Germany, standards [Societies, Medical], adverse effects [Antiparkinson Agents], Humans, Societies, Medical, therapeutic use [Antiparkinson Agents], Parkinson Disease, drug therapy [Parkinson Disease], Substance Withdrawal Syndrome, Neurology, standards [Deep Brain Stimulation], standards [Neurology], standards [Practice Guidelines as Topic], Practice Guidelines as Topic, Antiparkinson Agents/therapeutic use [MeSH] ; Deep Brain Stimulation/standards [MeSH] ; Humans [MeSH] ; Therapy ; Parkinson Disease/therapy [MeSH] ; Antiparkinson Agents/adverse effects [MeSH] ; Practice Guidelines as Topic/standards [MeSH] ; Parkinson Disease/diagnosis [MeSH] ; Neurology/standards [MeSH] ; Parkinson Disease/drug therapy [MeSH] ; Deep brain stimulation withdrawal syndrome ; Akinetic crisis ; Societies, Medical/standards [MeSH] ; Germany [MeSH] ; Dopamine agonist withdrawal syndrome ; Review ; Substance Withdrawal Syndrome/diagnosis [MeSH] ; German Parkinson Guideline ; Diagnostic criteria, Therapy, diagnosis [Parkinson Disease], ddc: ddc:610
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