Research Objective The Study indicates that research provides chemo preventive effects Significant reduction in cancerous cells Indicative suppression of growth of tumor Quantifying and analyzing DNA damage in individual cells Introduction The purpose of the research study on cancer is to develop safe and effective methods to prevent, detect, diagnose, treat, and, ultimately, cure the collections of diseases we call cancer. Ideas for new cancer research studies are often inspired by findings from earlier research, research on other cancers, and even findings from research done on other diseases, such as diabetes or immune disorders. Its aim is to reduce the number of deaths from cancer. Summary of Findings Mammary tumors were successfully induced by oral administration. PHPC Compound produced significant anti-cancer activity, which was evident by significant reduction in incidence of solid tumor in PHPC Compound treated group. This was clearly indicated by means of results of tumor as compared to diseases control group and histopathology of mammary gland. PHPC Compound significantly increased the level of antioxidant enzymes like SOD and catalase, which were reduced in case of diseased controlled groups. This indicates chemo-protective effect of PHPC Compound. OBJECTIVE To study the anti cancer activity of Polyherbal formulation PHPC Compound. SCOPE The scope covers cytotoxicity study by using MTT assay on MCF-7 human breast cancer Research Methodology A Report Of Anti-cancer activity (In vitro) of herbal formulation-PHPC Compound A Report Of Acute Oral Toxicity Study Of PHPC Compound To evaluate protective effect of in 5-fluorouracil (5 FU) induced toxicity A Report Of Sub-chronic (90-days) Oral Toxicity Study of PHPC Compound A Report of Study of PHPC Compound in 7,12-Dimethylbenz(a)anthracene induced Breast cancer Evaluation of effect of formulation “PHPC Compound” on cellular DNA damage Protective effect of PHPC Compound against 5-FU induced toxicity study Keywords:- cancer, cancer diagnosis, cancer treatment, cancer research, cancer cell, oncology, tumor, breast cancer, chemotherapy, radiation therapy, tumor size, DNA, tumor growth, research and development, cancer phase, metastatic, malignanat cells