
A mixed-integer, non-linear model is developed for designing robust global supply chain networks under uncertainty. Six resilience strategies are proposed to mitigate the risk of correlated disruptions. In addition, an efficient parallel Taguchi-based memetic algorithm is developed that incorporates a customized hybrid parallel adaptive large neighborhood search. Fitness landscape analysis is used to determine an effective selection of neighborhood structures, while the upper bound found by Lagrangian relaxation heuristic is used to evaluate quality of solutions and effectiveness of the proposed metaheuristic. The model is solved for a real-life case of a global medical device manufacturer to extract managerial insights.
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