Aim. Reduction of the magnetic field induction to the level of modern sanitary standards by means of active screening in residential old buildings which are located near existing typical overhead power lines are considered. Active shielding of the magnetic field inside a single-storey and multi-storey building is considered. During the design the number, configurations, spatial arrangement of the shielding windings, as well as the currents in the shielding windings were determined. Methodology. The design problem for the system of active shielding reduced to solving the minimax vector optimization problem. The vector of objective function in this minimax problem is calculated based on Biot-Savart's law. The solution of this problem is based on multi-agent optimization algorithms. Results. The results of theoretical and experimental studies of the systems of active shielding of the magnetic field generated by various overhead power lines inside a single and multi-storey building are presented. Originality. The possibility of reducing the induction of the initial magnetic field inside the shielded space to the level of sanitary standards is shown. Practical value. From the point of view of the practical implementation for a reasonable choice of the number and spatial arrangement of shielding windings of systems for active shielding of the magnetic field generated by various overhead power lines inside residential buildings of different storey’s are given.