The Data Mining Techniques provide useful ways to generate desired patterns from the large data and establish relations between them to solve problems using data analysis. This paper focuses on a data mining algorithm called CURE, and its applications on Health Care and Video data. Big Data consists of large volume, ever growing Datasets with multiple sources. Big Data in Health Care is an emerging area which helps healthcare organizations for their analytics and reporting needs. Data Mining Techniques, predictive analytics, and prescriptive analytics are some of the methods to analyze the healthcare data and derive useful information for several applications. On the other hand, Video Processing is an emerging area of research which gives rise to variety of applications like object tracking, shot detection, Video Summarization, etc. This paper discusses the application of CURE clustering algorithm on Video Processing for generating Video Summary and application of the same algorithm on Big Data Health Care Dataset for deriving disease related information.