Relevance. The article presents the broad overview of scientific publishing related to ecological problems of Voronezh reservoir. Issues connected with chemical, microbiological, biotic and other problems of this reservoir that impact the Voronezh population well-being were discussed in many monographs, articles, and reports at scientific conferences. Also, there are many scientific publications, reports, monographs and dissertations that were dedicated to health and well-being of population of Voronezh city. However, this comprehensive information still lacks integrated approach to solution of the whole range of problems related to the Voronezh reservoir eco/geo/system components. Methods. The authors tried to analyze publications based on the water body scientific researches outcomes, and to propose their own versions of environmental problems’ solution. Results. This review can be helpful not only in further planning on the Voronezh reservoir status research but in preparing practical measures on its improving.