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Biomedical Photonics
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INFLUENCE OF PHOTOACTIVATED ROSE BENGAL ON MICROCIRCULATION

descriptionPublicationkeyboard_double_arrow_right Article 06 Dec 2017Publisher:Russian Photodynamic AssociationJournal:Biomedical Photonics, volume 6, pages 11-15 (issn: 2413-9432, Copyright policy )
Authors: T. G. Gryshachova; I. A. Mikhailova; A. V. Struy; S. G. Chephu; N. N. Petrishchev;

doi: 10.24931/2413-9432-2017-6-3-11-15

INFLUENCE OF PHOTOACTIVATED ROSE BENGAL ON MICROCIRCULATION

Abstract

The study of mean blood velocity changes in rat mesenteric venules (15–30 µm) due to photoactivation (λ = 532 nm, 0,175 W/cm2, 300 s) of i.v. injected Rose Bengal (17 mg/kg) is represented in the article. Using in vivo biomicroscopy the progressive decrease of mean blood velocity both during the laser irradiation and after it was registered. The calculation of thermal effects in the irradiated part of microvessel due to laser absorption by hemoglobin and Rose Bengal showed the rise of temperature was not exceed 0.2оC as compared to initial level. Thus, thermal effect has nearly no significant influence on microvascular disturbances caused by Rose Bengal photoactivation.

Keywords

микроциркуляция, photosensitizer, бенгальский розовый, средняя скорость кровотока, фотосенсибилизатор, microcirculation, rose bengal, mean blood velocity, Medical technology, R855-855.5

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
Average
gold