Global South populations, firms and governments play a key role in redefining the relationship between sciences, technologies and markets on an international scale. Forces shaping the future of global technoscience emerge from unexpected places, prompting a reassessment of global power processes. This volume contains rich case studies studying technoscientific globalization ‘from below’ drawn from fieldwork in Asia, Latin America and Africa, examining the interplay between technology, power, and society at the global scale. The cases are grounded in postcolonial Science and Technology Studies and address a range of topics including pharmaceutical markets, scientific developments and digital practices. This approach illuminates the multiple creative ways in which subaltern players appropriate, divert, overturn or bypass prevailing views on technology and market construction.