The current COVID 19 pandemic has highlighted the need for flexibility in the provision of nursing care of extremely ill patients. A new proposition for a clinical adaptability suite of rooms is presented which can be multi-functional to accommodate surgery, intensive care or isolation. A literature review of medical and nursing practice and requirements and a case study analysis are presented. We explore the physical changes to the built environment which have taken place during the pandemic and undertake an analysis of the environmental and infrastructure requirements of a clinically adaptable room. Finally, we present the initial ideas for an innovative case study which considers how we design, manufacture and assemble advanced, versatile and multi-functional hospital settings. The resulting proposed clinically adaptable room reflects new models of clinical care. We explore the common denominators which show similar requirements in terms of medical equipment infrastructure, ventilation requirements and sterile conditions. A more sustainable alternative scenario shows the potential for reorganization and alteration to existing facilities.