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Clinical anatomy and operative surgery
Article . 2017 . Peer-reviewed
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THE CHANGES IN INDICES OF ION REGULATIVE RENAL FUNCTION IN MATURE AND IMMATURE RATS DEPENDING ON DIFFERENT ACTIVITY OF THE PINEAL GLAND

Authors: Vepriuk, Y M; Tovkach, Y V; Rogovyi, Yu E; Rykhlo, I S;

THE CHANGES IN INDICES OF ION REGULATIVE RENAL FUNCTION IN MATURE AND IMMATURE RATS DEPENDING ON DIFFERENT ACTIVITY OF THE PINEAL GLAND

Abstract

Известно, что основной механизм действия мелатонина – антиоксидантный. Проявляет антистрессовое, иммуномодулирующее действия, облегчает адаптацию при изменении климатических условий, влияет на синхронизацию колебательных процессов в организме, также является ингибитором полового созревания, причем противогонадное его действие не является прямым. Мелатонин обеспечивает защиту белковых молекул от окислительного повреждения и является одной из главных молекул в системе защиты организма от окислительного стресса и может проявлять защитные свойства на канальцы почек. В условиях гиперфункции шишковидной железы наблюдали менее существенные потери ионов натрия, однако на фоне гипофункции потеря ионов натрия была более существенной.

 It has commonly been assumed that the fundamental mechanism of action of melatonin is antioxidative one. The functions of melatonin involve numerous physiological processes, including antistress and immune modulate action, inhibition of pubescence, seasonal changes and circadian rhythm regulation. Melatonin also protects protein molecules from oxidative damage and is one of the basic molecules in protection system of the body, which can provide protective actions for tubules of the kidney. Under conditions of pineal gland hyperfunction less significant loss of sodium ions was observed, while against the background of pineal gland hypofunction loss of sodium ions was more essential.

Відомо, що основний механізм дії мелатоніну – антиоксидантний. Виявляє значну антистресову, імуномодулювальну дії, полегшує адаптацію при зміні кліматичних умов, впливає на синхронізацію коливальних процесів в організмі, також є інгібітором статевого дозрівання, причому не є прямою протигонадною його дія. Мелатонін забезпечує захист білкових молекул від окиснювального пошкодження і є однією із головних молекул в системі захисту організму від окиснювального стресу та може виявляти захисні властивості на канальці нирок. За умов гіперфункції шишкоподібної залози спостерігали менш істотні втрати іонів натрію, проте на тлі гіпофункції втрата іонів натрію була більш істотною. 

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Keywords

kidneys; mature rats; immature rats; pineal gland, нирки; статевозрілі щури; статевонезрілі щури; пінеальна залоза, почки; половозрелые крысы; неполовозрелые крысы; шишковидная железа

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
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