Objective: determination of epidemiological peculiarities of acute intestinal infections outbreak incidence in Ukraine for the period 2014-2017. Materials and methods: Applying descriptive and analytical techniques of an epidemiological research method and statistical methods, using materials of the official statutory records of the Ministry of Health of Ukraine, the nature of acute intestinal infection outbreaks by etiology, transmission routes and affected cohort groups was investigated. Result and discussion: At the current stage AII outbreaks are registered every year and throughout Ukraine. Herewith, their specific gravity in total diarrheal infection incidence, excluding shigellosis and salmonellosis, is insignificant. Outbreak incidence levels in the industrial and tourist centres of Ukraine exceed similar rates in other regions by several times. Salmonelloses dominate in the nosological structure of outbreak incidence. The majority of outbreaks is transmitted by food. Most of diarrheal infection outbreaks are connected with catering facilities and children’s pre-school institutions, as well as with visiting festive occasions arranged at home. A rise in outbreak incidence is observed from May till September. Rotaviral enteritis outbreaks are more frequently registered in January through March. Conclusion: The detected peculiarities of acute intestinal infection outbreak incidence shall be considered when developing regional programs of epidemiological surveillance over diarrheal infections. Bangladesh Journal of Medical Science Vol.18(1) 2019 p.73-77