Abstract: The article presents the results of a factorial PEST study of the development of social entrepreneurship in Ukraine. The aim of the study is to identify the main features and factors of development of social entrepreneurship in the light of the concept of social responsibility and the use of opportunities and resources of large enterprises to support social entrepreneurship. Systematization of the processed information sources shows that in recent years a significant amount of information on the development of social entrepreneurship in Ukraine has been accumulated. However, the problem of discrepancy between the amount of theoretical knowledge and the practical needs to act in the face of constant challenges remains relevant. The methodology of PEST analysis includes desk research, expert surveys, preparation of generalizations, calculations based on survey results, measures for the development of social entrepreneurship for the coming years (in the context of factors that experts consider the most important). The object of the research is the theoretical and practical aspects of the development of social entrepreneurship in the context of the concept of social responsibility. The task of the study is to identify the main features and factors of development of social entrepreneurship in the light of the concept of social responsibility and the use of opportunities and resources of large enterprises to support it. The methodological basis of the study is the basic theoretical and methodological provisions of economic sciences, the legal legislation of Ukraine, the works of leading domestic and foreign scientists in the field of economics, marketing and management of social enterprises and social responsibility of business. According to the results of the study, the essence, features and directions of development of social entrepreneurship in Ukraine, as well as the insufficient pace and scale of its distribution, are determined. The forms of involvement of large enterprises in promoting the development of social entrepreneurship in the context of social responsibility in Ukraine are substantiated. Scope of the research results The results of the study can be used in enterprises, regional communities, regional and state authorities, and non-governmental organizations. The results of the study can be 1) PEST factors for the development of social entrepreneurship in Ukraine are unstable; 2) instability is best expressed in groups of political and socio-cultural factors (the risk of socio-economic and political instability is related to the institutional capacity of civil society organizations and the potential for decentralization); 3) the main challenges are grouped by economic factors (e.g., dependence on international donors, insufficient budget funding, low competitiveness); 4) there is an imbalance in the group of technological factors (access to online resources has the greatest weight among all the factors proposed for assessment in the PEST analysis format, while the lack of necessary equipment and premises has the least weight); 5) strengthening the organizational capacity of civil society organizations, decentralization of power within the framework of administrative reform and the use of online resources; 6) socio-economic and political instability, prevalence of social problems, weak definition of social entrepreneurship, violation of legislation, dependence on international sources of funding, lack of strong teams, development strategies, financial and marketing plans, lack of tools for assessing social entrepreneurship; 7) none of the analyzed factors was named by the experts as such that may disappear in the future. The authors associate actions for the further development of social entrepreneurship mainly with the possibilities of decentralization. The obtained results are useful for the development of strategies for the development of social entrepreneurship at the regional level and for the application of the PEST analysis method in further monitoring studies.