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Journal of Research in Pharmacy
Article . 2025 . Peer-reviewed
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Development and validation of an electroanalytical method for the quantification of antiviral molnupiravir and its application to the pharmaceutical sample

Authors: Ateş, Ali Kemal;

Development and validation of an electroanalytical method for the quantification of antiviral molnupiravir and its application to the pharmaceutical sample

Abstract

In this study, a sensitive, fast, economical, and practical voltammetric method was developed for analysing molnupiravir (MLP), an antiviral drug extensively used during the COVID-19 pandemic, without the need for modifying the glassy carbon (GC) electrode surface. During the electroanalysis, an oxidation peak for MLP was detected at 0.72555 V on the GC electrode. The method exhibited linearity across a concentration range of 1 - 250 µM for MLP with 0.33 µM of detection limit. Furthermore, with a 99.81% recovery from its pharmaceutical form, the method's effectiveness was validated. These results strongly indicate that this method is suitable for routine quality control of molnupiravir and may serve as a model for analysing other antiviral drugs.

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Keywords

Pharmaceutical Analytical Chemistry, Eczacılıkta Analitik Kimya, Antiviral agent;molnupiravir;electroanalytical chemistry;differential pulse voltammetry

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
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