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A lipid hydrogel to transport and release an anti-HIV-1 peptide into vaginal mucosa

Authors: Noèlia Loza-Rodríguez; Aina Millán-Sánchez; Aleix Benítez; Ramon Pons; María José Gómara; Isabel Haro; Meritxell Genescà; +1 Authors

A lipid hydrogel to transport and release an anti-HIV-1 peptide into vaginal mucosa

Abstract

A graphical representation of the development process of a lipidic hydrogel loaded with an anti-HIV peptide for pre-exposure prophylaxis: characterization, ex vivo mucosa permeation, and efficacy testing in vaginal mucosa.

Keywords

Peptide antiretroviral therapy, CHEMICALS AND DRUGS::Amino Acids, Peptides, and Proteins::Peptides, Otros calificadores::Otros calificadores::Otros calificadores::/prevención & control, Other subheadings::Other subheadings::/therapeutic use, Otros calificadores::Otros calificadores::/uso terapéutico, ORGANISMS::Viruses::RNA Viruses::Retroviridae::Lentivirus::Lentiviruses, Primate::HIV, ENFERMEDADES::virosis::virosis::enfermedades de transmisión sexual::enfermedades virales de transmisión sexual::infecciones por VIH, Infeccions per VIH - Prevenció, HIV inhibitor peptide (RE-E1P47), DISEASES::Virus Diseases::Virus Diseases::Sexually Transmitted Diseases::Sexually Transmitted Diseases, Viral::HIV Infections, CHEMICALS AND DRUGS::Pharmaceutical Preparations::Dosage Forms::Colloids::Gels::Hydrogels, COMPUESTOS QUÍMICOS Y DROGAS::preparados farmacéuticos::formas farmacéuticas::coloides::geles::hidrogeles, CHEMICALS AND DRUGS::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Antiviral Agents::Anti-Retroviral Agents, COMPUESTOS QUÍMICOS Y DROGAS::acciones y usos químicos::acciones farmacológicas::usos terapéuticos::antiinfecciosos::antivíricos::antirretrovirales, COMPUESTOS QUÍMICOS Y DROGAS::aminoácidos, péptidos y proteínas::péptidos, VIH (Virus), Otros calificadores::Otros calificadores::Otros calificadores::/administración & dosificación, Antiretrovirals - Ús terapèutic, Other subheadings::Other subheadings::Other subheadings::/prevention & control, Other subheadings::Other subheadings::Other subheadings::/administration & dosage, Ensure healthy lives and promote well-being for all at all ages, Pèptids - Ús terapèutic, ORGANISMOS::virus::virus ARN::Retroviridae::Lentivirus::Lentivirus de los primates::VIH

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    influence
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green
gold