The work evaluated the regulatory-adaptive status in male students aged 18 to 21 years (60). The control group comprised persons of the same age, not specifically engaged in additional physical activity, but only in the framework of the curriculum (2 hours per week - 35 people). The main group consisted of students with enhanced physical activity, engaged in sports sections , with 25 people (volleyball, football, basketball, wrestling, track and field, swimming). The purpose of this study was to quantify the effect of exercise on the regulatory-adaptive status of the students. The results indicate a significant increase in regulatory-adaptive status in individuals with increased physical activity (index of the regulatoryadaptive status was made 104,16, and in the control group, 38.3 per). Increased physical activity in sports clubs has a positive effect on regulatory-adaptive status of the organism.