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Antibiotics and Chemotherapy
Article . 2023
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Antibiotics and Chemotherapy
Article . 2023
Data sources: DOAJ
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The Results of Preclinical Studies Assessing the Effect of Riamilovir on the Reproductive Function and Postnatal Growth of Offspring in Laboratory Animals

Authors: A. U. Sabitov; L. P. Larionov; M. N. Dobrinskaya; O. V. Ledyankina; A. V. Osipenko; I. E. Valamina; E. V. Philippova; +1 Authors

The Results of Preclinical Studies Assessing the Effect of Riamilovir on the Reproductive Function and Postnatal Growth of Offspring in Laboratory Animals

Abstract

The paper presents the results of extended preclinical studies demonstrating the safety using the direct-acting antiviral drug Riamilovir in immature white rats. Riamilovir did not show any toxic effects on the growth of animals, their fertility, behavior, hematological and biochemical parameters, as well as morphology of visceral organs when used in a course. According to the results of the studies, Ramilovir can be recommended for multicenter clinical trials in adolescents and children of younger age groups.

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Keywords

риамиловир, safety, доклинические исследования, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, immature laboratory animals, безопасность, неполовозрелые животные, riamilovir, лабораторные, preclinical studies, RC254-282

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold
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Cancer Research