Bioprotective effect of zinc in macro- and nanoaquachelate form on embryonal development of rats in conditions of lead intoxication
Copyright policy )Bioprotective effect of zinc in macro- and nanoaquachelate form on embryonal development of rats in conditions of lead intoxication
The article presents results of studied influence of low doses of lead and zinc (nanozinc) on embryonal development in a la¬boratory experiment on rats. Negative influence of lead on pregnancy of laboratory animals, manifested in violation of the physiological dynamics of the rectal temperature and decrease in body weight gain was revealed. Embryotoxic effect of low doses of lead results in increased fetal mortality by 2.16 times compared to the control group of animals, de¬terioration of the morphometric indices of fetuses, violation of placentogenesis. Simultaneous injections of zinc on back¬ground of lead intoxication causes a protective effect on the body of pregnant rats and embryonal development of the offspring, more pronounced for zinc citrate, received by using aquananotehnology, as compared to zinc chloride. Thus, by morphometry indices, male fetuses were more sensitive to prenatal lead exposure in comparison to female fetuses.
embryotoxicity, lead, experiment, R, Medicine, nanometals, УДК 618.2-053.13-092.9:612.014.46:669.018.674, heavy metals, ембріотоксичність; експеримент; важкі метали; нанометали; свинець, embryotoxicity; experiment; heavy metals; nanometals; lead
embryotoxicity, lead, experiment, R, Medicine, nanometals, УДК 618.2-053.13-092.9:612.014.46:669.018.674, heavy metals, ембріотоксичність; експеримент; важкі метали; нанометали; свинець, embryotoxicity; experiment; heavy metals; nanometals; lead
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