Anthrax animal burial sites and potentially hazardous as regards anthrax territories (PHT) of the three municipal entities in the Far Eastern Federal District (FEFD) were exposed to the Amur River flood (the Amur River basin, river inflows, and near-by territories), the emergency situation in August-September 2013. In order to estimate epizootiological-epidemiological situation on the infection carried out was retrospective analysis of morbidity rates among the population and the livestock animals of the region. Studied were the peculiarities of anthrax spatial distribution and sanitary conditions of PHT and animal burial sites (including anthrax ones). Laboratory investigations of soil and bone samples for the presence of Bacillus anthracis were conducted. Thus based on the results obtained the short-term forecast for epidemiological situation development in the post-flood period was worked out, and a complex of anti-anthrax actions was recommended.