Ceruloplasmin, Copper, Selenium, Iron, Zinc, and Manganese Levels in Normal and Sulfite Oxidase Deficient Rat Plasma: Effects of Sulfite Exposure
Copyright policy )Ceruloplasmin, Copper, Selenium, Iron, Zinc, and Manganese Levels in Normal and Sulfite Oxidase Deficient Rat Plasma: Effects of Sulfite Exposure
A noticeable effect of sulfite treatment was observed on the plasma ceruloplasmin ferroxidase activity of rats with normal sulfite oxidase activity when compared to normal controls. The plasma levels of selenium, iron, and zinc were unaffected by sulfite in normal and sulfite oxidase (SOX)-deficient rats. While plasma level of Mn was decreasing, plasma Cu level increased in SOX-deficient rats. Treating SOX-deficient groups with sulfite did not alter plasma level of Mn but made plasma level of Cu back to its normal level. This is the first evidence that Cu and Mn status were affected in experimental sulfite oxidase deficiency induced by low molybdenum diet with tungsten addition deserving further research to determine the underlying mechanisms of these observations in experimental sulfite oxidase deficiency.
- Pamukkale University Turkey
- Süleyman Şah University Turkey
Male, antioxidant, tungsten, Atomic, Sulfite oxidase, iron, molybdenum, sulfite, rat, animal, genetics, selenium, atomic absorption spectrometry, zinc, article, trace element, Ceruloplasmin, ceruloplasmin, enzyme activity, sulfite oxidase deficiency, Zinc, Spectrophotometry, manganese, blood sampling, enzyme deficiency, 570, Iron, animal experiment, 610, animal tissue, enzyme blood level, Selenium, sulfite oxidase, Animals; Ceruloplasmin/*metabolism; Copper/blood; Iron/blood; Male; Manganese/blood; Rats; Selenium/blood; Spectrophotometry, Atomic; Sulfite Oxidase/genetics; Sulfites/*administration & dosage; Trace Elements/*blood; Zinc/blood, male, blood, Animals, Sulfites, controlled study, Manganese, nonhuman, Rattus, animal model, Spectrophotometry, Atomic, Sulfite Oxidase, amine oxidase (flavin containing), vitamin supplementation, Rats, Trace Elements, Sulfite, copper, Rat plasma, diet, metabolism, Copper
Male, antioxidant, tungsten, Atomic, Sulfite oxidase, iron, molybdenum, sulfite, rat, animal, genetics, selenium, atomic absorption spectrometry, zinc, article, trace element, Ceruloplasmin, ceruloplasmin, enzyme activity, sulfite oxidase deficiency, Zinc, Spectrophotometry, manganese, blood sampling, enzyme deficiency, 570, Iron, animal experiment, 610, animal tissue, enzyme blood level, Selenium, sulfite oxidase, Animals; Ceruloplasmin/*metabolism; Copper/blood; Iron/blood; Male; Manganese/blood; Rats; Selenium/blood; Spectrophotometry, Atomic; Sulfite Oxidase/genetics; Sulfites/*administration & dosage; Trace Elements/*blood; Zinc/blood, male, blood, Animals, Sulfites, controlled study, Manganese, nonhuman, Rattus, animal model, Spectrophotometry, Atomic, Sulfite Oxidase, amine oxidase (flavin containing), vitamin supplementation, Rats, Trace Elements, Sulfite, copper, Rat plasma, diet, metabolism, Copper
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