The object of research is the mechanism of industrial restructuring of Ukraine. One of the most problematic places of its formation is the insufficient methodical and methodological support of methods and tools for the impact of economic transformations on the development of industrial enterprises. One of such methods is the choice of a development strategy focused on overcoming technological gaps. The study used theoretical and methodological studies aimed at justifying the conditions for sustainable growth of enterprises on an innovative basis. It is shown that the economic transformations that have occurred in Ukraine are due to the evolutionary processes of the formation of a market-type economy and the intensification of globalization processes in the global economy. This necessitated the formation of new mechanisms for managing the development of industrial enterprises. For this it is necessary at the macro level: to ensure an effective combination of the state organization of the economy and market self-organization; to overcome the gap between the real sector of the economy and financial markets and achieve an economically viable level of virtualization; to eliminate regional differentiation; to create conditions for eliminating significant income inequality; to ensure consistency between the newly created institutions that operate and the changes taking place in the economic system; to strengthen the socialization and moral content of economic relations. In conditions when the state will play an active regulatory role in economic processes, it is possible to ensure the transition of industrial enterprises to an innovative and strategic level of development on the basis of the proposed approaches. This is due to the fact that the proposed mechanism of the influence of economic transformations on the development of industrial enterprises has a number of application features, in particular, affects the innovative activity of enterprises. This ensures the possibility of obtaining an increase in market value, business activity of enterprises. Compared with similar methods of managing economic transformations, this method provides such advantages as strategic orientation, flexibility and adaptability of management decisions in enterprises.