Cerebroprotective and Regenerative Effects of Alkaloid Z77 under Conditions of Brain Ischemia
Copyright policy )Cerebroprotective and Regenerative Effects of Alkaloid Z77 under Conditions of Brain Ischemia
We studied the psychopharmacological effects of atisine-type diterpene alkaloid Z77 in a rat model of cerebral ischemia. Pronounced cerebroprotective effect was found consisting in normalization of the orienting and exploratory activity and conditioned behavior associated with significant correction of morphological changes in the brain. The direct stimulatory effect of Z77 on neural stem cells was shown in vitro.
- National Research University of Electronic Technology Russian Federation
- National Research Tomsk State University Russian Federation
- Russian Academy
Male, церебропротективные препараты, стволовые клетки, Regenerative Medicine, Brain Ischemia, Rats, Alkaloids, Neuroprotective Agents, церебральная ишемия, Neural Stem Cells, алкалоиды, Animals, медицина регенеративная
Male, церебропротективные препараты, стволовые клетки, Regenerative Medicine, Brain Ischemia, Rats, Alkaloids, Neuroprotective Agents, церебральная ишемия, Neural Stem Cells, алкалоиды, Animals, медицина регенеративная
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