The focus of this paper is on facilities with multiple sections where the material transport between sections occurs through corridors. A Mixed Integer Linear Programming (MILP) formulation for the Operating Theater Layout problem is proposed. The formulation uses a multi-goal approach to optimize two objectives: the first quantitative objective minimizes the interdepartmental traveling costs, whereas the second qualitative objective maximizes the closeness of the facilities. The presented model determines the position and orientation of each activity according to the OT international standards. The applicability of the model is demonstrated on four illustrative examples using commercial optimization software.