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Evaluación de la acción cicatrizante del Vimang® en un modelo experimental de ratas con quemaduras

Authors: Sady Valdés Mesa; Dailys Delgado Sánchez; Abraham Ismael Beato Canfux; Juan Manuel Cantón Fábregas; Mariela Lázara Machado Fernández;

Evaluación de la acción cicatrizante del Vimang® en un modelo experimental de ratas con quemaduras

Abstract

Introducción: Es usual el empleo de productos derivados de las plantas, para el tratamiento de las quemaduras. Objetivo: Evaluar la acción cicatrizante de la crema de Vimang® al 1,2 % en un modelo experimental de quemadura en ratas. Métodos: Se realizó un estudio experimental en un modelo de ratas con quemaduras de segundo grado, profundas, que se les aplicó la crema de Vimang® al 1,2 %. Se utilizaron 105 ratas machos en 3 grupos: Controles positivos (con sulfadiazina de plata), negativo (placebo) y el expuesto al Vimang®. La investigación se realizó en 2 etapas: Estandarización del modelo biológico y determinación del efecto cicatrizante del Vimang en crema. Resultados: El grupo tratado con Vimang® presentó una reducción del área de la quemadura más rápida, la cantidad de animales epitelizados fue de 18 (85,7 %) vs. 15 (83,3 %) en el grupo con sulfadiazina de plata. El tiempo de cicatrización para el grupo Vimang® tuvo una mediana de 11 días vs. 14 en el grupo sulfadiazina de plata y 15 en el grupo con placebo. Conclusiones : El Vimang® en el modelo animal de quemadura en ratas reduce en menor tiempo el área de la lesión, comparada con la sulfadiazina de plata y el placebo.

Keywords

Medicine (General), R5-920, R, medicina natural y tradicional., Medicine, Vimang, Mangifera indica L

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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