Objective:In this study, we aimed to compare the endometrial suction biopsy with Pipelle® and endometrial curettage (D&C) findings from patients with abnormal uterine bleeding and/or endometrial thickness to observe the possible influencing factors on ESB’s diagnostic value.Method:In Tekirdağ Community Hospital and Gynecology Clinic, data were retrospectively collected from hospital registry. 122 patients who had abnormal uterine bleeding and/or endometrial thickness were selected and from all cases, endometrial biopsies were taken with Pipelle® and D&C methods at the same time. In conclusion, pathologic results of two methods were compared.Results:Pathology results were as follows: By Pipelle®, 44 patients (36.1%) were found with endometrial polyp, 26 patients (21.3%) with endometrial atrophy, 31 patients (25.4%) with proliferative endometrium, 11 patients (9%) with secretory endometrium, 4 patients (3.3%) with endometrial carcinoma, 1 patient (0.8%) with hyperplasia without atypia, 2 patients (1.6%) with inflammation; by D&C, 55 patients (45.1%) were found with polyp, 20 patients (16.4%) with endometrial atrophy, 34 patients (27.9%) with proliferative endometrium, 9 patients (7.4%) with secretory endometrium, 4 patients (3.3%) with endometrial carcinoma, 1 patient (0.8%) with hyperplasia without atypia, 2 patients (1.6%) with inflammation. Correlations between two methods were found as 97.6%, 95.3%, 91.7%, 98.3%, 100%, 100%, and 100% for proliferative endometrium, atrophy, polyp, secretory endometrium, endometrial cancer, hyperplasia without atypia and inflammation, respectively. Discorrelations between two diagnostic methods were more commonly seen in endometrial polyp pathology.Conclusion:Our study findings revealed very high correlations between the pathology results of Pipelle® and D&C procedures. Pipelle®, with the advantages of being a simple outpatient procedure and having less complication rates, can be preferred over D&C reliably in most clinic situations. On the other hand, D&C method should be preferred in cases of endometrial polyp pathologies due to increased discorrelation rates and biopsy failures in Pipelle® biopsy.