The article is devoted to the development a system of training future entrepreneurs for commercialization of scientific developments, which come from the Institute of Applied Physics the Russian Academy of Sciences (IAF RAS). In the thorough analysis of the existing models of commercialization of scientific research was carried out, which are used in Russia and abroad. It was noted that at the moment there are 7 basic models of commercialization, which are the most successful. The most successful projects in the commercialization of scientific research IAF RAS were studied in the article. They are ZAO NPP "boom", NTK OOO "Medusa" and "Center of scientific and technological development". As a result of this study it was proposed to implement the developed commercialization model it was asked to create a separate structural unit within the IAF RAS - the Center for Technology Transfer.