
The molecular effects of trimetazidine and mildronate were investigated in patients with stable effort angina, Functional Class (FC) I-III. The comparison criteria included blood activity and concentrations of the main products of free-radical oxidation and the components of Krebs cycle and anti-oxidant system. Proteomic methods were also used. Trimetazidine and mildronate could be recommended as cardio-protectors in primary and secondary prevention of FC I-III coronary heart disease.
proteomics, free-radical oxidation, cytochemistry, trimetazidine, RC666-701, mildronate, Diseases of the circulatory (Cardiovascular) system, coronary heart disease
proteomics, free-radical oxidation, cytochemistry, trimetazidine, RC666-701, mildronate, Diseases of the circulatory (Cardiovascular) system, coronary heart disease
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