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COMPARING MOLECULAR EFFECTS OF VARIOUS CYTOPROTECTORS IN COMPLEX THERAPY OF CORONARY HEART DISEASE

Authors: E. A. Kartashova;

COMPARING MOLECULAR EFFECTS OF VARIOUS CYTOPROTECTORS IN COMPLEX THERAPY OF CORONARY HEART DISEASE

Abstract

The molecular effects of trimetazidine and mildronate were investigated in patients with stable effort angina, Functional Class (FC) I-III. The comparison criteria included blood activity and concentrations of the main products of free-radical oxidation and the components of Krebs cycle and anti-oxidant system. Proteomic methods were also used. Trimetazidine and mildronate could be recommended as cardio-protectors in primary and secondary prevention of FC I-III coronary heart disease.

Keywords

proteomics, free-radical oxidation, cytochemistry, trimetazidine, RC666-701, mildronate, Diseases of the circulatory (Cardiovascular) system, coronary heart disease

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold