Bullous pemphigoid is an acquired auto-immune blistering disease, which affects predominantly the elderly. It is rare in children and exceptional in infant. To our knowledge only ten cases were previously reported. We report a new case of a previously healthy six months old infant who presented with erythemato-vesico-bullous cutaneous lesions over a period of six days. Histology and immunofluorescence led to the diagnosis of bullous pemphigoid. Therapy with systemic and topic corticosteroids resulted in a good outcome.