Background: Economic growth has always been known as one of the fundamental ideals of governments and an indicator to assess their performance. Achieving economic growth more than anything, depends on right recognition of potential pathways and the factors influencing it. One of the factors affecting economic growth is workforce health which forms the basis of human capital in combination with education. This study surveyed the effects of household health expenditure on economic growth and evaluated some other impressive factors on growth of Iranian provinces. Methods: This theoretical, scientific study used a method derived from Romer's endogenous growth model. The mentioned model was selected after technical studies and econometric tests using panel data approach, i.e. blending time series of 2000-2007 with cross-sectional data from 27 provinces of Iran. Results: Findings of this survey proved the positive effect of household health expenditure growth and government investment expenditure on economic growth of provinces of Iran. Moreover, the results showed a negative relationship between consumer price index (CPI) and the economic growth of each province. Conclusion: Household health care expenditure had a significant effect on economic growth of Iranian provinces. Considering the proportion of this expenditure of household budget compared to other countries, economic growth and development of different provinces can be achieved through improving health care. Keywords: Economic Development; Health Care Economics and Organizations; Health Expenditures; Manpower.