We developed diagnostic protocol and studied cervical diseases in 733 women with HIV. There were found high incidence of sexual transmitted diseases and multifocal papilloma in these patients. We describe colposcopical signs of cervical papilloma virus infection in HIV-positive women. We suppose that low information content of cervical cytology could be connected with concomitant infections. We also found that HIV is not eliminated but cause to dysplasia of cervical epithelium. That is why we suppose to optimal to pay an attention to cervical neoplasms in women with HIV-PVI association. Severity of observed cervical changes was depended on the associations with sexual transmitted infections, CD4+ lymphocytes level and total virus load.