To meet the trade demand of China and Russia for pipeline gas of China–Russia Eastern Gas Pipeline Project, effectively simulate the pipeline characteristic parameters and their changing trends at the custody transfer point of the pipeline crossing section, and achieve the calculation and judgment on the daily average custody transfer pressure and the daily minimum custody transfer pressure, the mathematical model was established according to the basic formulas and state equations for hydraulic calculation and thermal calculation stimulated in the agreement between the two countries.Newton iteration method was used to perform the adaptive correction on the pipeline roughness and the environmental heat transfer coefficient, and the software with independent intellectual property rights for the simulation and calculation of pressure and temperature at the transfer point was developed in China.Comparing the software simulation results with the Russian software simulation results, it can be concluded that the software calculation accuracy meets the requirements of the relevant agreements of China–Russia Eastern Gas Pipeline Project, demonstrating the reliability of the software calculation results.Therefore, the software is capable of simulating and calculating the process parameters at the custody transfer point of China–Russia Eastern Gas Pipeline Project, as well as the supervision and control of the natural gas custody transfer.