For women increase of cardiovascular disease (CVD) in menopausal period is characteristic. Epidemiological and clinical researches reveal distinctions in development of atherosclerotic defeat of vessels in the person depending on a floor. Along with the general risk factors, such as the hereditary anamnesis, a food, adiposity, smoking, low physical activity, a diabetes and an arterial hypertensia (АH), is available for women a unique risk factor of cardiovascular diseases - development of deficiency of an estrogen in menopausal period.