
A simple direct method for the synthesis of lumazine-6,7-diamines (9, 25-27) from uracil-5,6-diamines (10-13) and methyl cyanoformimidate (24) was found. Various nucleophilic displacement reactions were performed with 7-chloro-1,3-dimethyllumazine-6-amine (17) leading to new 6,7-disubstituted 1,3- dimethyllumazine derivatives (18-23).
condensation and nucleophilic displacement reactions, Crystallography, QD901-999, lumazine-6,7 -diamines, methyl cyanoformimidate
condensation and nucleophilic displacement reactions, Crystallography, QD901-999, lumazine-6,7 -diamines, methyl cyanoformimidate
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