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Evaluation of the toxicity of Brachiaria decumbens in rabbits

Authors: Faccin, Tatiane Cargnin; Pupin, Rayane Chitolina; Leal, Paula Velozo; dos Santos, Ariany Carvalho; de Lima, Stephanie Carrelo; Ferreira, Valquiria Barbosa Nantes; Garcez, Walmir Silva; +1 Authors

Evaluation of the toxicity of Brachiaria decumbens in rabbits

Abstract

ABSTRACT. Faccin T.C., Pupin R.C., Leal P.V., Santos A.C., Lima S.C., Ferreira V.B.N, Garcez W.S. & Lemos R.A.A. Evaluation of the toxicity of Brachiaria decumbens in rabbits. [Avaliação do efeito tóxico de Brachiaria decumbens em coelhos.] Revista Brasileira de Medicina Veterinária, 38(2):143-146, 2016. Laboratório de Anatomia Patológica, Faculdade de Medicina Veterinária e Zootecnia, Universidade Federal de Mato Grosso do Sul, Av. Senador Filinto Müller, 2443, Campo Grande, MS 79074-460, Brasil. E-mail: tatifaccin@hotmail.com The objective of this study was to evaluate the sensitivity of rabbits to poisoning by Brachiaria decumbens and the possible use of this animal species as an experimental model for studies on poisoning by this forage in livestock. The experiment was conducted during the dry season with 12 rabbits. The treated group of nine animals was kept in a paddock of B. decumbens, and the control group with three rabbits was kept in cages and received cabbage (Brassica oleracea). Samples of young, mature, and old leaves and seeds of B. decumbens were collected for quantification of the saponin protodioscin. Euthanasia of rabbits from both groups was performed 30, 60 and 90 days after the introduction of the treated group to the pasture. The rabbits showed no clinical signs and no macroscopic or histological findings characteristic of Brachiaria spp. poisoning. Both groups gained weight during the experiment. The concentration of the protodioscin (% dry matter) ranged from 0.87% to 2.72% (mean ± standard deviation: 1.95 ± 0.50%) in young leaves, 0.93% to 2.74% (1.71 ± 0.42%) in mature leaves, 0.59% to 1.66% (1.10 ± 0.25%) in old leaves and 0.11% to 0.28% (0.20 ± 0.05%) in seeds. These results demonstrate that B. decumbens is palatable to rabbits and that rabbits are not susceptible to poisoning by Brachiaria spp. with saponin concentrations that are toxic for sheep.

O objetivo do presente trabalho foi avaliar a sensibilidade dos coelhos à intoxicação por Brachiaria decumbens e o possível emprego desta espécie animal como modelo experimental para o estudo da intoxicação por esta forrageira em animais de produção. O experimento foi realizado durante a época seca do ano com 12 coelhos. O grupo tratado, com nove animais foi mantido em piquete de B. decumbens e o grupo controle, com três coelhos, em gaiolas recebendo repolho (Brassica oleracea). Amostras de sementes e folhas novas, maduras e senescentes de B. decumbens foram coletadas para quantificação da saponina protodioscina. A eutanásia dos coelhos de ambos os grupos foi realizada 30, 60 e 90 dias após a introdução dos animais do grupo tratado na pastagem. Os coelhos não apresentaram sinais clínicos, nem achados macroscó- picos ou histológicos característicos de intoxica- ção por Brachiaria spp. Os dois grupos ganharam peso durante o experimento. A concentração de protodioscina (% matéria seca) variou de 0,87% a 2,72% (média ± desvio padrão: 1,95 ± 0,50) nas folhas novas, de 0,93% a 2,74% (1,71 ± 0,42) nas folhas maduras, de 0,59% a 1,66% (1,10 ± 0,25) nas folhas senescentes e de 0,11% a 0,28% (0,20 ± 0,05) nas sementes. Estes resultados demonstram que B. decumbens é palatável para coelhos. Conclui-se que os coelhos não são susceptíveis à intoxicação por Brachiaria spp. com concentrações de saponinas que são tóxicas para ovinos.

Keywords

Brachiaria spp., intoxicação por plantas, experimental model, poisonous plants, modelo experimental, protodioscina, protodioscin

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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