This thesis is concerned with the formulation and preparation of hydrogels for the subsequent application as a device to capture and stabilise volatile thiols contained within sweat. Using the well documented ability of hydrogels to absorb both water and small molecules, the absorption storage and extraction of thiol solutions was investigated. \ud \ud The stability of individual free thiols was investigated in solution at two different temperature over the course of three weeks. Utilizing the well-known ability of thiol reactivity with maleimides, the reaction of Dibromomaleimide (DBM) with thiols known to be present within sweat was investigated and the stability of these thiol DBM derivatives investigated. \ud A thiol release reaction with phenol thiol was investigated to highlight the possibility of releasing the original thiol for quantification. \ud Quantitative analysis of the thiol compounds was carried out via GC-FID, with the analysis of the thiol DBM derivatives carried out via HPLC with UV detector. \ud The desired formulation of a NaAMPS hydrogel was investigated by varying water concentration, crosslinker concentration and Mn for the crosslinker. Testing was undertaken to determine the hydrogels physical properties to enable a suitable formulation to be selected for further investigation in the stability of the thiols. DBM incorporated hydrogels were also formulated and tested. Investigations into the react of thiol with DBM in the hydrogels was carried out. \ud \ud Hydrogels were tested against textile patches to determine their stability of the free thiol and recovery of the thiol. These were compared to the free thiol solution stability. Further studies looked into the stability of the thiol DBM complex both in solution and from a hydrogel. An organo acetonitrile based gel was investigated to determine if these gels had better stability rates when compared to the normal hydrogels. Mechanical testing of the organogels was carried out. \ud