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The group investigates blood clotting mechanisms and particularly the causes of thrombosis and haemophilia. Our research includes the biochemistry and structure of coagulation proteins, the molecular genetics of thrombophilia and haemophilia and the cellular biology of blood vessels. Diseases of blood vessels and thrombosis are among the most prevalent causes of premature death in Western society. Advances in the basic science of these conditions are urgently needed to find ways of preventing the onset of disease and to improve the treatment of affected individuals.
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