The HiCure project seeks to build capacities to develop an integrated curricula in Health Informatics as pathways within the undergraduate degrees of the faculties of Health and Information Technology, using a student-centred adaptive learning approach based on the bologna processes. It aims to develop two pathways, integrated within the current curricula, to bring continuity and achieve harmony across the programmes. The project will develop 12 courses in total. Each pathway will include eight courses, four of these courses will be common across the two pathways, while four of each of the eight courses will be unique to each pathway. These two pathways will be deployed at the four participating partner universities, two in Palestine (P1: BZU, P3:HU) and two in Jordan (P4:JUST, P5:HaU). The uniqueness of this approach, that to meet the multidisciplinary needs of the two domains, it will develop an innovative user-centred adaptive learning to create an integrated curricula and enable the four universities to integrate the new developed courses within their degrees addressing variations, yet meeting their own specified key learning outcomes. The importance of Health Informatics to be part of the undergraduate training as integral part of their educational skills, is critical to advance the health domain towards evidence-based practices, in the region, which is currently almost non-existent. These skills are essential to solidify the deeper understanding of the value and importance of health informatics not only to their speciality, but also their profession, work and practice. They will promote the uptake and implementation of health information systems to become essential part of their profession as enabling mechanisms to improve the quality of health. Thus one key objective of HiCure is to develop capacity of members of faculty in Health Informatics and create undergraduate pathways to ensure sustainability and lasting impact.