T2DMOF is targeted at offering an extremely skilled and promising emerging researcher with a PhD in Organic Chemistry and an outstanding track record a highest quality training through research in the cross-disciplinary, supra-sectoral, and burgeoning field of 2D electronic materials by developing a green solution to address the global challenge of energy generation. Thermoelectric generators can convert temperature differences directly into electrical voltages via the Seebeck effect. However, the currently used thermoelectric materials (inorganic/conducting polymers) have critical drawbacks, as they contain highly toxic elements, require high micro/nanofabrication costs, display limited stability, etc. T2DMOF aims to develop a novel class of two-dimensional conjugated metal–organic frameworks (2D c-MOFs) to overcome the above-mentioned challenges in conventional thermoelectric materials, while proposing reliable structure–property relationships to guide the design of next-generation MOF-based thermoelectric materials. The diversity of 2D c-MOF synthesis methods (film/powder) enables planar flexible or columnar array thermoelectric generators to be realized in view of different practical application scenarios. T2DMOF’s overall objective is to train the fellow to become a mature and independent top scientist and to prepare him for a leading position in academia or industry in Europe.