Start a new DMP in Loading
The project leader invented a new device for hypothermic pulsed perfusion, named INOVAGRAFT (2 patents, Inserm Prize 2015 for Innovation), which would drastically enhance the duration of grafts transport. Associated with a new carrier of O2 derived from marine worms (HEMO2life®, patented by the company Hemarina), INOVAGRAFT could be at the origin of a paradigm shift in heart transplantation, with the possibilities: - (1) to greatly extend the preservation time, - (2) to allow the use of hearts from donors in circulatory arrest (Donor Cardiac Death). INOVAGRAFT- HEMO2life® would therefore partly overcome the dramatic shortage of cardiac grafts. INOVAGRAFT is an imaging compatible device that would also enable the evaluation of the graft viability by multimodal imaging: MRI, Ultrasound, X, and PET in order to characterize: - (a) edema and tissue hardening - (b) microperfusion and vascular permeability - (c) energy status of the graft.
<script type="text/javascript">
<!--
document.write('<div id="oa_widget"></div>');
document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=anr_________::93062c78f8e4f78cbb07ebfbd00335da&type=result"></script>');
-->
</script>