Astatine-211 is a promising radioisotope as a therapeutic tool due to the alpha particle emitted upon it radioactive decay. In order to use this property, it is necessary to bind it chemically to a carrier molecule able to transport it to the diseased cells to eradicate. Alpha particles being highly energetic but having a short penetration in tissues, their destructive action is limited to a small volume, therefore preventing damages to surrounding healthy tissues. However, the lack of knowledge on the basic chemistry on this element limits the available strategies to bind astatine efficiently to the carrier molecules of interest. The formation of a covalent astatine-carbon bond is frequently used, but this kind of bond is not robust enough to consider its use on human patient with sufficient safety. This project aims at carrying out an upstream research in order to assess the potential of alternative strategies to the astatine-carbon bond, which relies herein on the formation of astatine-metal bonds, and to determine if this approach has the potential for applications in nuclear medicine.