Assessing current and future biodiversity patterns, and their underlying drivers is of crucial importance to develop relevant conservation programs and promote sustainable development and human well-being. While biodiversity conservation research and actions yet mostly focus solely on taxonomic diversity, considering the diversity of organismal traits (functional) and evolutionary lineages (phylogenetic) offers promise for effective conservation and the maintenance of resilient ecosystems to global change. Indeed, taxonomic, functional, and phylogenetic facets do not necessarily react at the same pace or scale, neither respond in the same way to drivers, especially anthropogenic perturbations. Knowledge about multifaceted biodiversity is still very fragmented which greatly limits our ability to anticipate current and future conservation needs. The main objective of INTEGRADIV is to develop an integrative approach to provide guidelines on how taxonomic, functional and phylogenetic facets of biodiversity should be encapsulated in realistic conservation plans. To achieve this, we will notably rely on the assessment of ecosystem integrity (its degree of preservation) and vulnerability to global change, based on an innovative quantification of trait-based and phylogenetic attributes distributions. INTEGRADIV will benefit from both existing and newly collected occurrences, life-traits and phylogenetic data to develop an innovative framework of biodiversity assessment considering multiple spatial scales (regional and euro-Mediterranean) and taxonomic groups Considering the diversity of trees, butterflies and birds in the Euro-Mediterranean biodiversity hotspot, the key questions INTEGRADIV will address are: 1)Where are the high-value biodiversity areas? 2)What is the level of ecological integrity of the Euro-Mediterranean forests? 3)How were shaped spatial patterns of biodiversity, and how high are they vulnerable to climate and land-use changes? INTEGRADIV will build on the answers to these questions to provide a prioritization scheme for guiding effective future conservation strategies that will integrate all facets of biodiversity with responsible use of public money. The prioritization tool aims to be implementable, to be used in the future for example with new data at a finer spatial resolution, or to test new societal constraints. To ensure that the project aligns with stakeholder needs, it will engage in a joint learning process at the science-practice-policy interface from the beginning of the project. INTEGRADIV results will be delivered to the stakeholder community through policy briefs, outreach publication and workshops all along the project.