Transported by currents, plastics strand on the coastal areas, important places of artisanal fisheries. Plastics can harbor pathogens that are involved in human epidemics. It is thus legitimate to ask whether these pathogens and their virulence & resistance genes (PVR) can be transferred to marine animals that ingest plastics, and potentially to human who consumes them. Plastics would thus play a role of vector. VectoPlastic implements a multidisciplinary approach to evaluate this role in a socio-ecosystem dependent on artisanal fisheries (Tule´ar, Madagascar). The objectives are to evaluate the transfer of PRV to 2 commercial species, their persistence from capture to sale on stalls, the perception of populations of the health risk related to plastics and their pathogens, and an integrated risk assessment; in order to define sensitization and management actions adapted to the socio-cultural context.