Evolution over the eons has made Nature a treasure trove of clever solutions to sustainability, resilience, and ways to efficiently utilize scarce resources. The Centre for Nature Inspired Engineering will draw lessons from nature to engineer innovative solutions to our grand challenges in energy, water, materials, health, and living space. Rather than imitating nature out of context or succumbing to superficial analogies, research at the Centre will take a decidedly scientific approach to uncover fundamental mechanisms underlying desirable traits, and apply these mechanisms to design and synthesise artificial systems that hereby borrow the traits of the natural model. The Centre will initially focus on three key mechanisms, as they are so prevalent in nature, amenable to practical implementation, and are expected to have transformational impact on urgent issues in sustainability and scalable manufacturing. These mechanisms are: (T1) "Hierarchical Transport Networks": the way nature bridges microscopic to macroscopic length scales in order to preserve the intricate microscopic or cellular function throughout (as in trees, lungs and the circulatory system); (T2) "Force Balancing": the balanced use of fundamental forces, e.g., electrostatic attraction/repulsion and geometrical confinement in microscopic spaces (as in protein channels in cell membranes, which trump artificial membranes in selective, high-permeation separation performance); and (T3) "Dynamic Self-Organisation": the creation of robust, adaptive and self-healing communities thanks to collective cooperation and emergence of complex structures out of much simpler individual components (as in bacterial communities and in biochemical cycles). Such nature-inspired, rather than narrowly biomimetic approach, allows us to marry advanced manufacturing capabilities and access to non-physiological conditions, with nature's versatile mechanisms that have been remarkably little employed in a rational, bespoke manner. High-performance computing and experimentation now allow us to unravel fundamental mechanisms, from the atomic to the macroscopic, in an unprecedented way, providing the required information to transcend empiricism, and guide practical realisations of nature-inspired designs. In first instance, three examples will be developed to validate each of the aforementioned natural mechanisms, and simultaneously apply them to problems of immediate relevance that tie in to the Grand Challenges in energy, water, materials and scalable manufacturing. These are: (1) robust, high-performance fuel cells with greatly reduced amount of precious catalyst, by using a lung-inspired architecture; (2) membranes for water desalination inspired by the mechanism of biological cell membranes; (3) high-performance functional materials, resp. architectural design (cities, buildings), informed by agent-based modelling on bacteria-inspired, resp. human communities, to identify roads to robust, adaptive complex systems. To meet these ambitious goals, the Centre assembles an interdisciplinary team of experts, from chemical and biochemical engineering, to computer science, architecture, materials, chemistry and genetics. The Centre researchers collaborate with, and seek advice from industrial partners from a wide range of industries, which accelerates practical implementation. The Centre has an open, outward looking mentality, inviting broader collaboration beyond the core at UCL. It will devote significant resources to explore the use of the validated nature-inspired mechanisms to other applications, and extend investigation to other natural mechanisms that may inform solutions to problems in sustainability and scalable manufacturing.

A 4-year multidisciplinary project aimed at minimising primary-energy use in UK industry is proposed, concerned with next-generation technological solutions, identifying the challenges, and assessing the opportunities and benefits (to different stakeholders) resulting from their optimal implementation. Around 20 companies from component manufacturers to industrial end-users have expressed an interest in supporting this project. With this industrial support, the team has the necessary access and is in a prime position to deliver real impact, culminating in the practical demonstration of these solutions. The proposed project is concerned with specific advancements to two selected energy-conversion technologies with integrated energy-storage capabilities, one for each of: 1) heat-to-power with organic Rankine cycle (ORC) devices; and 2) heat-to-cooling with absorption refrigeration (AR) devices. These technological solutions are capable of recovering and utilising thermal energy from a diverse range of sources in industrial applications. The heat input can come from highly efficient distributed combined heat & power (CHP) units, conventional or renewable sources (solar, geothermal, biomass/gas), or be wasted from industrial processes. With regards to the latter, at least 17% of all UK industrial energy-use is estimated as being wasted as heat, of which only 17% is considered economically recoverable with currently available technology. The successful implementation of these technologies would increase the potential for waste-heat utilisation by a factor of 3.5, from 17% with current technologies to close to 60%. The in-built, by design, capacity for low-cost thermal storage acts to buffer energy or temperature fluctuations inherent to most real heat sources, allowing smaller conversion devices (for the same average input) and more efficient operation of those devices closer to their design points for longer periods. This will greatly improve the economic proposition of implementing these conversion solutions by simultaneously reducing capital and maintenance costs, and improving performance. The technologies of interest are promising but are not economically viable currently in the vast majority of applications with >5-20 year paybacks at best. The project involves targeting and resolving pre-identified 'bottleneck' aspects of each technology that can enable step-improvements in maximising performance per unit capital cost. The goal is to enable the widespread uptake of these technologies and their optimal integration with existing energy systems and energy-efficiency strategies, leading to drastic increases performance while lowering costs, thus reducing payback to 3-5 years. It is intended that technological step-changes will be attained by unlocking the synergistic potential of optimised, application-tailored fluids for high efficiency and power, and of innovative components including advanced heat-exchanger configurations and architectures in order to increase thermal transport while simultaneously reducing component size and cost. Important system-level components are included in the project, whose objective is to assess the impact of incorporating these systems in targeted industrial settings, examine technoeconomic feasibility, and identify opportunities relating to optimal integration, control and operation to maximise in-use performance. A dynamic, interactive whole-energy-integration design and assessment platform will be developed to accelerate the implementation of the technological advances, feeding into specific case-studies and facilitating direct recommendations to industry. Only two international research teams are capable of developing the necessary tools that combine multiscale state-of-the-art molecular thermodynamic theories for fluids, detailed energy-conversion ORC and AR models, and incorporating these into whole-energy-system optimisation platforms. This is truly a world-leading development.

Environmental and economic concerns related to the excessive use of fossil fuels, together with opportunities in circular economy and carbon negative technologies are paving the way for a fundamental reorganisation of the chemical industry. Oil refineries are being redesigned to couple petrochemical processes with bio-based productions and new thermo-chemical technologies more suited for small-scale operation. In this context, the invention of new (or restructured) processes for the synthesis of renewable intermediates, such as olefins generated from biomass is of crucial importance, since these molecules are fundamental building blocks for polymers, fuels and chemical industry. In order to unlock the transition to bio-substitutes in energy and manufacturing sectors, resource efficiency, process flexibility and intensification are of critical importance. To achieve these goals, we propose to employ a Nature-Inspired Solution (NIS) methodology, as a systematic platform for innovation and to inform transformative technology. The NIS methodology will be used to design and optimise modular bio-syngas conversion methods to manufacture "green" chemical products, including bio-olefins, at a scale suitable for decentralised applications. The research will focus on the novel concept of Sorption Enhanced Olefin Synthesis (SEOS), and the integrated design and performance of key system components (Synthesis Reactor - Catalysts Configuration - Life Cycle Analysis) to provide information on the underpinning reaction mechanisms, engineering performance and system dynamics that will facilitate deployment of future bio-based manufacturing plants.