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Fundación Para la Gestión de la Investigación Biomédica de Cádiz

Fundación Para la Gestión de la Investigación Biomédica de Cádiz

4 Projects, page 1 of 1
  • Funder: European Commission Project Code: 247835
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  • Funder: European Commission Project Code: 256369
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  • Funder: European Commission Project Code: 101183057
    Funder Contribution: 1,104,000 EUR

    The research and innovation program, named GALATEA, stands as a pioneering venture targeting infant nutrition through the development of a digital twin of human milk. The program brings together interdisciplinary expertise from computational modeling, bioinformatics, clinical neonatology, experimental lab techniques, and engineered bioreactors for cell culturing, forming a consortium dedicated to advancing our understanding of human milk's complexities. The overarching objective is to create a sophisticated simulation platform that mirrors the intricate composition of human milk, allowing for the formulation of personalized nutrition plans for infants, particularly those born prematurely. GALATEA's innovative spirit extends beyond computational models, encompassing experimental lab work utilizing bioreactors and cutting-edge techniques like metabolomics and proteomics. The program's mobility component facilitates cross-disciplinary learning among participating organizations, fostering collaborative knowledge exchange. Anticipated outcomes include enhanced health outcomes for newborns, a deeper understanding of human milk for the advancement of artificial milk formulations, and the establishment of a robust research community dedicated to neonatal nutrition. GALATEA represents a holistic and innovative approach to the fundamental challenge of infant nutrition, setting new standards for personalized strategies and collaborative interdisciplinary efforts.

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  • Funder: European Commission Project Code: 956394
    Overall Budget: 3,835,850 EURFunder Contribution: 3,835,850 EUR

    Prematurity exponentially increases the risk for an altered neurodevelopmental outcomes in childhood and adolescence. Many survivors children, face a lifetime of disability. Despite the advances in neonatal care have greatly improved survival of preterm born infants even at extremely low gestational ages we are now at a period of steadiness where no further improvement in long-term neurodevelopmental outcome is seen. The impact of these sequelae affects not only at a personal and familiar level but also poses a significant burden on society. Early diagnostics of brain injury and/or brain dysmaturation as well as early detection of impairments are important strategies to improve the well-being of children and their families allowing for developmental monitoring and medical evaluation of the specific type of disorder that affects a child and optimize therapeutics options. In this context, PARENT is a vision for a multidisciplinary approach to develop diagnostic and predictive platforms focused on newborn motor/cognitive impairments. PARENT will make a critical contribution towards an open neurodevelopmental disease diagnostic software infrastructure by interlinking disciplines from clinical data, neuroimaging collection and processing, biomarkers, data fusion, machine learning applied to clinical data, novel prediction algorithms. To best leverage the data potential, PARENT envisions an easy-to-use software infrastructure which provides integrated databases, validated algorithms components and platforms built upon them. This vision can be included in the more general paradigm of evidence-based medicine, personalized medicine and patient center care, as well as decision support systems in clinical field. PARENT combines the efforts of a multidisciplinary network of 10 leading European research groups, industry partners, pediatric hospitals and parents’ association to develop a technological infrastructure that will train 15 Early Stage Researchers.

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