Crop wild relatives (CWR) are wild plant taxa closely related to a crop. They represent an important source of genetic diversity for the improvement of agronomic traits. In the context of the One Health Initiative, temperate fruit trees are essential for human nutrition and health, yet CWR resources have hitherto been underused. Moreover, fruit tree long lifespan and a current production dominated by a few cultivars make them particularly vulnerable to the effects of global changes. To address this challenge, the FRUITDIV project will monitor, characterise, use, and conserve the diversity of emblematic fruit tree CWR, with a particular emphasis on Malus, Pyrus and Prunus. To better characterise the genetic and phenotypic diversity of CWR fruit trees and identify favourable traits for future introgression into cultivars, FRUITDIV will use a combination of floristic, ethnogeography and population genomics on genebanks and historical European hotspots of diversity. We will then develop new multiomics-based breeding strategies that combine marker-assisted introgression for traits of interest (e.g. resilience, resistance to pests and diseases, fruit quality) with pangenomic prediction and a reduction of CWR-associated genetic load. In addition to breeding programs, FRUITDIV will also work with networks of farmers and associations to help characterise CWR progeny in various pedo-climatic conditions in Europe. An European-wide online platform that provides genotyping and phenotyping data for free will be implemented to promote the use of CWR genitors by breeders and farmers and help disseminate plant material of interest for various usages and cultivation systems. Overall, the FRUITDIV multi-actor approach involving geneticists, forestry officers, germplasm curators, farmers and citizens, will foster the in- and ex-situ conservation of CWR and promote sustainable agricultural practices across Europe.

The COVID-19 pandemic has affected educational systems worldwide, leading to the near-total closures of all formal learning settings. This is a good time to expand opportunities in non-formal and informal settings. xFORMAL project aims at creating a framework in which science and technology meet citizens of all ages in an informal intergenerational educational setting, based on a platform and a game devoted to the common European cultural heritage. The key ingredients of the project are: the history of ancient Europe (partly taught in formal education), the landscape (typically, a non-formal learning base), the heutagogic approach, the virtual/augmented reality (generally recognised as an informal-learning tool), and the sharing of knowledge and experiences between SSH and ICT researchers in an intersectoral setting. The proposed actions target the creation of new partnerships in local communities to foster improved education for all citizens following the heutagogy approach. This project aims at supporting a range of research, dissemination and exploitation activities based on collaboration between educational providers, associations, enterprises, and civil society in order to become an agent of community well-being; encourage families to become real partners in educational life and activities; actively involve professionals from enterprises and civil and wider society in bringing real-life projects to the civil society; and encourage policymakers to the mainstream of good practices and insights into policies, and hence sustainability and impact beyond the lifetime of funding. It is expected that in the short term the development of xFORMAL partnerships between academic and non-academic institutions will contribute to a more scientifically interested and literate society and citizens of all ages with a better awareness of and interest in a cultural common heritage. In the long-term, it will contribute towards ERA objectives of increasing the number of scientists.

Over 30% of EU citizens at vulnerable stages and situations in life are at increased risk to transgress from healthy weight to overweight and further to obesity. Though many interventions to tackle obesity have been proposed, they have rarely been effective. The aim of HealthyW8 is to advance the efficacy of current and future efforts and investments in obesity prevention initiatives across Europe. Most interventions suffer from not adapting to personal context (e.g. socioeconomic aspects, host-biological factors, environment, dietary preferences, fitness level etc.), focus only on diet or physical activity alone, do especially overlook emotional aspects, and fail to engage and motivate the user. Thus, initiatives on obesity prevention in policy and practice are often of marginal impact. HealthyW8 will address these shortcomings by iteratively developing, together with stakeholders, a digital-based healthy lifestyle recommender for evidence-based, tailored interventions and tools including a human digital twin to bridge the gap between science, societal actors and stakeholders (e.g. healthcare professionals, food industries, policymakers) and EU citizens. The targeted populations are those undergoing transitions, i.e. schoolchildren (5-10 y, and their parents), young adults (18-25 y) and the elderly (>65 y). In the mid-term, we estimate that with 200,000 HealthyW8 users, we will prevent 10,000 obesity cases/y. In the long run, the impact will be maximized through adopting the project’s proposed methodology, platform and tools by as many EU institutions and entities as possible. HealthyW8 is a highly experienced, synergistic and complementary consortium that will built on a previously developed digital dietary app (LIFANA) and draw on transdisciplinary research in pan-EU multicentre pilots and long-term randomized control trials to achieve its overarching objective of increasing impact of current and future obesity prevention interventions and policies in the EU.